Visceral mobilization can lyse and prevent peritoneal adhesions in a rat model.

نویسندگان

  • Geoffrey M Bove
  • Susan L Chapelle
چکیده

OBJECTIVE Peritoneal adhesions are almost ubiquitous following surgery. Peritoneal adhesions can lead to bowel obstruction, digestive problems, infertility, and pain, resulting in many hospital readmissions. Many approaches have been used to prevent or treat adhesions, but none offer reliable results. A method that consistently prevented or treated adhesions would benefit many patients. We hypothesized that an anatomically-based visceral mobilization, designed to promote normal mobility of the abdominal contents, could manually lyse and prevent surgically-induced adhesions. MATERIAL AND METHODS Cecal and abdominal wall abrasion was used to induce adhesions in 3 groups of 10 rats (Control, Lysis, and Preventive). All rats were evaluated 7 days following surgery. On postoperative day 7, unsedated rats in the Lysis group were treated using visceral mobilization, consisting of digital palpation, efforts to manually lyse restrictions, and mobilization of their abdominal walls and viscera. This was followed by immediate post-mortem adhesion evaluation. The rats in the Preventive group were treated daily in a similar fashion, starting the day after surgery. Adhesions in the Control rats were evaluated 7 days after surgery without any visceral mobilization. RESULTS The therapist could palpate adhesions between the cecum and other viscera or the abdominal wall. Adhesion severity and number of adhesions were significantly lower in the Preventive group compared to other groups. In the Lysis and Preventive groups there were clear signs of disrupted adhesions. CONCLUSIONS These initial observations support visceral mobilization may have a role in the prevention and treatment of post-operative adhesions.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Effect of Heparin in Prevention of Experimental Abdominal Adhesions in Rat

Objective- Study on the effect of heparin in prevention of abdominal adhesions following abdominal surgery in rat. Design- Experimental design. Animals-Twenty male rats with average weight of 248 ± 5 gr. Procedures- Animals were randomly divided into two equal groups of 10 rats (A and B). After induction of anesthesia, a midline abdominal incision was made and intestines were manipulated ...

متن کامل

A survey on the influence of intra- peritoneal injection of hydrocortisone in the rate of intra abdominal adhesion bands in rats

  Occurrence of adhesions after pelvic and abdominal surgery is a well known problem. Previous surgical procedures are by far the most common cause of intra abdominal a adhesion. In over  10℅ of infertile women, adhesion formation is the main cause of their problem. Moreover postoperative adhesions are the most common cause of intestinal obstruction in the Western world. Although the cause of ...

متن کامل

I-19: The Selective Vitamin D Receptor Agonist Elocalcitol Reduces Development of Endometriosis and Formation of Peritoneal Adhesion in A Mouse Model

Background: Endometriosis is a chronic disorder characterized by the presence of endometrial tissue outside the uterus. Endometrial cells from retrograde menstruation implant on peritoneal surfaces and elicit an inflammatory response, associated with angiogenesis, fibrosis, neuronal infiltration, and anatomical distortion. Affecting an estimated 176 million women worldwide, the condition is sti...

متن کامل

Novel thermosensitive hydrogel for preventing formation of abdominal adhesions

Adhesions can form after almost any type of abdominal surgery. Postoperative adhesions can be prevented by improved surgical techniques, such as reducing surgical trauma, preventing ischemia, and avoiding exposure of the peritoneal cavity to foreign materials. Although improved surgical techniques can potentially reduce formation of adhesions, they cannot be eliminated completely. Therefore, fi...

متن کامل

Effect of Sargassum sp. extract on preventing abdominal adhesions in female rat

Background: Studies have shown that abdominal adhesions occur due to an oxidative stress by ROS. Sargassum sp. extract contains many antioxidative compounds that might be utilized to interrupt this process. This study intends to study the efficacy of Sargassum sp. extract on preventing abdominal adhesions. Methods: In this study, 20 female rats were divided into two groups. Group 1 receive Sarg...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:
  • Journal of bodywork and movement therapies

دوره 16 1  شماره 

صفحات  -

تاریخ انتشار 2012